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Human pre-mRNA 3'-end processing machinery database
Overall statistics
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all % |
IUR % |
secondary structure % |
α helix % |
β sheet % |
low complexity % |
inside of domains |
43.78 |
4.49 |
23.26 |
14.35 |
8.91 |
3.72 |
outside of domains |
56.22 |
72.68 |
21.25 |
15.29 |
5.96 |
55.18 |
Three most frequent domains in 3'-end processing proteins:
- a) RRM domain (RNA recognition motif) from PABP-1 (residues 1-190, pdb code: 4F02);
- b) WD40 domain of WDR33 which adopts a 7-bladed beta-propeller fold (residues 1-405, pdb code: 1VYH);
- c) zinc finger of CPSF4 protein (fragment 61-126, pdbcode: 2D9N).
Known domains in pre-mRNA 3'-end processing
Detailed statistics for domains as they are stored in PFAM for
pre-mRNA 3'-end processing proteins. Fragments corresponding to domains are assessed against secondary structure, IUP, low complexity predictions (for
details about methods used go to FAQ).
Contact: Lukasz Kozlowski
This work was supported by Polish Ministry of Science and Higher Education (grant NN301 190139).
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