Intrinsically unstructured disorder predictions for human pre-mRNA 3'-end processing machinery

Sub-complexes    CPSF
   CstF
   CFIm
   CFIIm
Other proteins    PABP-1
   PAPOLA
   RPB1
   PP-1A
   PP-1B
   Symplekin
   WDR82
   SSU72
   RBBP6

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Summary

Based on the Ward et al. 2004, it is expected that ~33% of protein residues are disordered in eukaryotic organisms. On the other hand, it is known that protein disorder is often over represented in so called "hub" proteins (interact with many proteins, presumably formatting complexes). Moreover, it is speculated that in many cases intrinsic flexibility of disordered proteins is important for their function. Here, we present results showing that protein disorder is highly abundant in the human pre-mRNA 3'-end processing machinery (disordered residues constitute up to 51%).
It should be stressed that in many cases disorder to order transition occurs while binding the partner. It means that disordered regions of many proteins from the complex can "adopt" temporally stable structure depending on the interacting partners and/or 3' mRNA processing stage.

Overall statistics

The longer protein is, the more residues are intrinsically disordered

Detailed statistics

Dataset	Number of proteins	% of disorder residues	% of proteins with IUR longer >30 aa	% of proteins with IUR longer >50 aa
all proteins (with isoforms)	60	51.43	81.67 (49 proteins)	73.33 (44 proteins)
all proteins (w/o isoforms)	33	47.30	81.82 (27 proteins)	75.76 (25 proteins)
complex with stechiometry¹	26	50.44	80.77 (21 proteins)	80.77 (21 proteins)
human spliceosome²	122	53.5 (44.0)	80.30 (98 proteins)	NA
human proteome³	26,385	21.60	35.20 (~9300 proteins)	21.9 (~5800 proteins)

Disorder in proteins

(to sort click on the column header)

Name	% disorder	Length
RPB1	30.1	1970
RBBP6	91.57	1792
RBBP6 2	91.3	1758
PCF11	86.82	1555
CPSF1	18.91	1444
WDR33	71.95	1337
Symplekin	33.91	1274
RBBP6 4	84.03	952
TUT1	59.5	874
CPSF2	28.64	782
PAPOLA	40.13	745
PAPOLG	36.55	736
CSTF3	21.9	717
PAPD1 2	45.65	712
CPSF3	14.33	684
Symplekin 2	38.04	673
PABP-4 3	50.15	660
PABP-4	46.27	644
PAPOLB	27.52	636
PABP-1	48.11	636
PABP-4 2	45.32	631
PABP-3	47.54	631
CSTF2T	79.38	616
FIP1L1	90.4	594
CPSF6 2	85.37	588
PAPD1	33.51	582
CSTF2	79.2	577
CSTF2 2	77.5	560
CPSF6	82.03	551
PABP-1 2	40.22	547
FIP1L1 3	87.31	520
CPSF7 3	81.32	514
PAPD4	31.61	484
PAPD4 2	30.0	480
CPSF6 3	80.13	478
CPSF7	78.77	471
CPSF7 2	78.14	462
CSTF1	6.96	431
CLP1	6.82	425
PABP-5	17.02	382
FIP1L1 4	85.45	378
CLP1 2	11.63	361
PP-1A 2	14.96	341
PABP-2 3	39.94	333
PP-1A	10.91	330
PP-1B	10.09	327
WDR33 2	11.96	326
WDR82	3.2	313
PABP-2	73.2	306
PABP-2 2	72.97	296
PAPOLA 2	9.12	285
CPSF4	45.35	269
WDR33 3	12.45	257
CPSF4 2	37.7	244
CPSF4 3	41.98	243
CPSF5	16.3	227
SSU72	2.06	194
SSU72 2	8.5	153
RBBP6 3	24.58	118
CSTF3 2	18.45	103

Flavors of protein disorder

Disorder vs secondary structure

Each protein may contain one or more segments which are disordered. Nevertheless, those segments still can have high content of secondary structure predicted by secondary structure prediction programs. It is suggested that disorder with high tendency to form secondary structure is a good indicator of a special case of protein disorder which easily change conformation from disordered to ordered if it binds to physiological partner. On the other side, if the region is predicted to be both disordered and with low secondary structure content it means that it will be disordered in physiological conditions (e.g. CTD of RNA polymerase II - RPB1)

'E' - beta sheet regions
'H' - alpha helix regions
'-' - other

Disorder vs low complexity

Another type of protein disorder is connected to low complexity regions. Such regions are biased in the amino acids composition which means that some amino acids are over represented and may be present in many repeats. A good example of this situation is C terminal domain of RBP1 protein CTD which is made up of many evolutionarily conserved heptapeptide repeats (YSPTSPS). Moreover, posttranslational modification of this region is important for function and thighly regulated (e.g. PP-1A and PP1B dephosphorylate it, while Ssu72p functions as a phosphatase with specificity for the fifth serine of the heptapeptide repeat).
'N' - low complexity regions
'-' - high complexity regions

Below, we present segments longer than 20 amino acids that are predicted to be disordered.

(to sort click on the column header)

Name	Length	Localization	secondary structure %	helix %	sheet %	low complexity %	secondary structure vs. low complexity
RBBP6	1470	323-1793	1.77	1.77	0.0	87.96	1........10........20........30.... KNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPL HHH-------------------------------- -------------NNNNNNNNNNNNNNNNNNNNNN MRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PFRDSDNKILPAAALASEHSKGTSSIAITALMEEK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN-- GYQVPVLGTPSLLGQSLLHGQLIPTTGPVRINTAR ----------------------------------- ----------------------------------- PGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSI ----------------------------------- ----------------------------------- NRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYPP ----------------------------------- -------------NNNNNNNNNNNNNNNNNNNNNN PPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN REEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEY -HHH--HH---------------------HHH--- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KKIQKERRRSFSRSKSPYSGSSYSRSSYTYSKSRS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSR ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFR ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYY ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GRSVDFRDPFEKERYREWERKYREWYEKYYKGYAA ---------------HHHHHHHHHHHHHHH----- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GAQPRPSANRENFSPERFLPLNIRNSPFTRGRRED ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN- YVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSK ----------------------------------- ----------------------------NNNNNNN EKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN LLETSRKSREPTGVEENKTDSLFVLPSRDDATPVR ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAH ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFES ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DKISLSAPAKKIKLNRETGKKIGSTENISNTKEPS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVD ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN YTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNND ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNN------- NTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQ ----------------------------------- -------------------NNNNNNNNNNNNNNNN PISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRD ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN YSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN LSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TYDTKRPNEETKSVDKNPCKDREKHVLEARNNKES ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQ ----------------------------------- NNNN----------------------NNNNNNNNN LSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGI ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVEL ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSVTV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN--
RBBP6 iso 2	1437	322-1759	1.81	1.81	0.0	87.75	1........10........20........30.... FKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQP HHHH------------------------------- --------------NNNNNNNNNNNNNNNNNNNNN LMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SSLAPPVSGNPSSAPAPVPDITATVSISVHSEKSD ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GPFRDSDNKILPAAALASEHSKGTSSIAITALMEE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN- KGYQVPVLGTPSLLGQSLLHGQLIPTTGPVRINTA ----------------------------------- ----------------------------------- RPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRS ----------------------------------- ----------------------------------- INRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYP ----------------------------------- --------------NNNNNNNNNNNNNNNNNNNNN PPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPL ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SREEFYREQRRLKEESKSPYSGSSYSRSSYTYSKS ---HHHHH--------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN FRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN YYGRSVDFRDPFEKERYREWERKYREWYEKYYKGY ---------------HHHHHHHHHHHHHHHHH--- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN AAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRR ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTK ----------------------------------- NNN---------------------------NNNNN SKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLN ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PELLETSRKSREPTGVEENKTDSLFVLPSRDDATP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN VRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN AHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDF ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EKDKISLSAPAKKIKLNRETGKKIGSTENISNTKE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTL ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN VDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNN----- NDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKS ----------------------------------- ---------------------NNNNNNNNNNNNNN TQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKD ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNF ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN QKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDH ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KATYDTKRPNEETKSVDKNPCKDREKHVLEARNNK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPK ----------------------------------- NNNNNN----------------------NNNNNNN PQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN AESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TV -- --
WDR33	918	418-1336	1.96	1.53	0.44	85.29	1........10........20........30.... NLLPGMSEDGVEYDDLEPNSLAVIPGMGIPEQLKL ----------------------E--------HHH- ----------------------------------- AMEQEQMGKDESNEIEMTIPGLDWGMEEVMQKDQK H-------------EEE----------HHH----- ----------------------------------- KVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVL ---------------HHHHHHH------------- ----------------------------------- NDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLE ----------------------------------- ------------------------------NNNNN QLKIERLAQKQVEQIQPPPSSGTPLLGPQPFPGQG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFR ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGI ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN QGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMI ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN MGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGR ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDD ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN FSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRR ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNRE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN MDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDR ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ASRGGGRG -------- NNNNNNNN
RBBP6 iso 4	632	321-953	0.63	0.63	0.0	94.62	1........10........20........30.... NFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQ HHHH------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSN ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN QSSLAPPVSGNPSSAPAPVPDITATVSISVHSEKS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DGPFRTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKS ----------------------------------- NNNNNNNNNNN----------NNNNNNNNNNNNNN TQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKD ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNF ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN QKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDH ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KATYDTKRPNEETKSVDKNPCKDREKHVLEARNNK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPK ----------------------------------- NNNNNN----------------------NNNNNNN PQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN AESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TV -- --
PCF11	631	693-1324	1.9	1.9	0.0	86.21	1........10........20........30.... FQYQEGVREEQRSPFNDRFPLKRPRYEDSDKPFVD H---------------------------------- ----------------------------------- SPASRFAGLDTNQRLTALAEDRPLFDGPSRPSVAR ----------------------------------- ----------------------------------- DGPTKMIFEGPNKLSPRIDGPPTPASLRFDGSPGQ ----------------------------------- -------------NNNNNNNNNNNNNNNNNNNNNN MGGGGPLRFEGPQGQLGGGCPLRFEGPPGPVGTPL ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RFEGPIGQAGGGGFRFEGSPGLRFEGSPGGLRFEG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PGGQPVGGLRFEGHRGQPVGGLRFEGPHGQPVGGL ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RFDNPRGQPVGGLRFEGGHGPSGAAIRFDGPHGQP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GGGIRFEGPLLQQGVGMRFEGPHGQSVAGLRFEGQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN HNQLGGNLRFEGPHGQPGVGIRFEGPLVQQGGGMR ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN FEGPSVPGGGLRIEGPLGQGGPRFEGCHALRFDGQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PGQPSLLPRFDGLHGQPGPRFERTPGQPGPQRFDG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PPGQQVQPRFDGVPQRFDGPQHQQASRFDIPLGLQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GTRFDNHPSQRLESVSFNQTGPYNDPPGNAFNAPS ----------------------------------- N----NNNNNNNNNNNNNNNNNNNNNNNNNNNNNN QGLQFQRHEQIFDSPQGPNFNGPHGPGNQSFSNPL ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NRASGHYFDEKNLQSSQFGNFGNIPAPMTVGNIQA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SQQVLSGVAQPVAFGQGQQFLPVHPQNPGFVQNPS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GALPKAYPDNHLSQVDVNELFSKLLKTGILKLSQT ----------------HHHHHHHHHH--------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DSATTQVSEVTAQPPPEEEEDQNEDQDVPDLTNFT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN V H N
PCF11	536	144-680	6.16	6.16	0.0	92.91	1........10........20........30.... AWPIKPLPPNVNTSSIHVNPKFLNKSPEEPSTPGT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN VVSSPSISTPPIVPDIQKNLTQEQLIRQQLLAKQK ----------------------HHHHHHHHHHHHH NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN QLLELQQKKLELELEQAKAQLAVSLSVQQETSNLG HHHHHHHH-HHHHHHHHHHHH-------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PGSAPSKLHVSQIPPMAVKAPHQVPVQSEKSRPGP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SLQIQDLKGTNRDPRLNRISQHSHGKDQSHRKEFL ----------------------------------- NNNNNNNN--NNNNNNNNNNNNNNNNNNNNNNNNN MNTLNQSDTKTSKTIPSEKLNSSKQEKSKSGEKIT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KKELDQLDSKSKSKSKSPSPLKNKLSHTKDLKNQE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SESMRLSDMNKRDPRLKKHLQDKTDGKDDDVKEKR ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KTAEKKDKDEHMKSSEHRLAGSRNKIINGIVQKQD ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TITEESEKQGTKPGRSSTRKRSRSRSPKSRSPIIH ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SPKRRDRRSPKRRQRSMSPTSTPKAGKIRQSGAKQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SHMEEFTPPSREDRNAKRSTKQDIRDPRRMKKTEE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ERPQETTNQHSTKSGTEPKENVENWQSSKSAKRWK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SGWEENKSLQQVDEHSKPPHLRHRESWSSTKGILS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PRAPKQQQHRLSVDANLQIPKELTLASKRELLQKT ----------------------------------- NNNNNNNNNN------------------------- SERLASGEITQ ----------- -----------
RPB1	487	1484-1971	0.0	0.0	0.0	90.14	1........10........20........30.... MEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMT ----------------------------------- ----------------------------------- PWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASD ----------------------------------- ------NNNNNNNNNNNNNNNNNNNNNNNNNNNNN ASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN MSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PASPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN -------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNN-------
CPSF6 iso 2	440	149-589	6.82	6.82	0.0	84.55	1........10........20........30.... LHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQMSGE ----------------------------------- --------------------------------NNN GKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GPAGPGGPPPPFPGNLIKHLVKGTRPLFLETRIPW ----------------------------------- NNNNNNNNNNNNNN--------------------- HMGHSIEEIPIFGLKAGQTPPRPPLGPPGPPGPPG ----------------------------------- ---------------NNNNNNNNNNNNNNNNNNNN PPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPH ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN VNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYD ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISS ----------------------HHHHH-------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SAISRAVSDASAGDYGSAIETLVTAISLIKQSKVS -HHH-------------HHHHHHHHHHHH------ NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ADDRCKVLISSLQDCLHGIESKSYGSGSRRERSRE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RDHSRSREKSRRHKSRSRDRHDDYYRERSRERERH ----------------------HHHHHH------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RDRDRDRDRERDREREYRHR ------------HHHH---- NNNNNNNNNNNNNNNNNNNN
CSTF2T	431	186-617	9.28	9.28	0.0	94.43	1........10........20........30.... IALKILHRKIHVTPLIPGKSQSVSVSGPGPGPGPG HHHHHH----------------------------- -------------NNNNNNNNNNNNNNNNNNNNNN LCPGPNVLLNQQNPPAPQPQHLARRPVKDIPPLMQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TPIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQL ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GMPGVGPVPLERGQVQMSDPRAPIPRGPVTPGGLP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RGPMIDQRGLPMDGRGGRDSRAMETRAMETEVLET ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RVMERRGMETCAMETRGMEARGMDARGLEMRGPVP --H-------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SSRGPMTGGIQGPGPINIGAGGPPQGPRQVPGISG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN VGNPGAGMQGTGIQGTGMQGAGIQGGGMQGAGIQG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN VSIQGGGIQGGGIQGASKQGGSQPSSFSPGQSQVT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PQDQEKAALIMQVLQLTADQIAMLPPEQRQSILIL ---HHHHHHHHHHHH--HHHHH---HHHHHHHHHH NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KEQIQKSTGAS HHHHHH----- -----------
FIP1L1	394	201-595	5.08	5.08	0.0	73.35	1........10........20........30.... VIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFK ----------------------------------- ----------------------------NNNNNNN VQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESP ----------------------------------- NNNNNNNNNNNNNNNNNNNNN-------------- DLRRLPGAIDVIGQTITISRVEGRRRANENSNIQV ----------------------------------- ----------------------------------- LSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFL ----------------------------------- ------------NNNNNNNNNNNNNNNNNNNNNNN PPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIES ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN- DTSKQWDYYARREKDRDRERDRDRERDRDRDRERE ----------------------------------- ----------NNNNNNNNNNNNNNNNNNNNNNNNN RTRERERERDHSPTPSVFNSDEERYRYREYAERGY ---------------------------HHHHH--- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ERHRASREKEERHRERRHREKEETRHKSSRSNSRR -------HHHHHHHHHHHHHH-H------------ NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ESTEATPAE --------- NNNN-----
CSTF2	391	187-578	9.97	9.97	0.0	91.05	1........10........20........30.... ALKILHRQTNIPTLIAGNPQPVHGAGPGSGSNVSM HHHHHHH---------------------------- ---------------NNNNNNNNNNNNNNNNNNNN NQQNPQAPQAQSLGGMHVNGAPPLMQASMQGGVPA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PGQMPAAVTGPGPGSLAPGGGMQAQVGMPGSGPVS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN MERGQVPMQDPRAAMQRGSLPANVPTPRGLLGDAP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHVPG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN HESRGPPPHELRGGPLPEPRPLMAEPRGPMLDQRG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PPLDGRGGRDPRGIDARGMEARAMEARGLDARGLE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ARAMEARAMEARAMEARAMEARAMEVRGMEARGMD ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TRGPVPGPRGPIPSGMQGPSPINMGAVVPQGSRQV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PVMQGTGMQGASIQGGSQPGGFSPGQNQVTPQDHE ---------------------------------HH NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQ HHHHHHHHHH--HHHHH----HHHHHHHHHHHHHH NNNNNNNNNNNNNNNNNNNNN-------------- KSTGAP H----- ------
CSTF2 iso 2	372	189-561	10.22	10.22	0.0	91.67	1........10........20........30.... KILHRQTNIPTLIAGNPQPVHGAGPGSGSNVSMNQ HHHHH------------------------------ -------------NNNNNNNNNNNNNNNNNNNNNN QNPQAPQAQSLGGVPAPGQMPAAVTGPGPGSLAPG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GGMQAQVGMPGSGPVSMERGQVPMQDPRAAMQRGS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN LPANVPTPRGLLGDAPNDPRGGTLLSVTGEVEPRG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN YLGPPHQGPPMHHVPGHESRGPPPHELRGGPLPEP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RPLMAEPRGPMLDQRGPPLDGRGGRDPRGIDARGM ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EARAMEARGLDARGLEARAMEARAMEARAMEARAM ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EARAMEVRGMEARGMDTRGPVPGPRGPIPSGMQGP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SPINMGAVVPQGSRQVPVMQGTGMQGASIQGGSQP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GGFSPGQNQVTPQDHEKAALIMQVLQLTADQIAML --------------HHHHHHHHHHHH--HHHHH-- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PPEQRQSILILKEQIQKSTGAP -HHHHHHHHHHHHHHHH----- NNNN------------------
FIP1L1 iso 3	336	185-521	7.44	7.44	0.0	67.26	1........10........20........30.... EVIPVTSTTNKITVQQGRTGNSEKETALPSTKAEF ----------------------------------- ----------------------------------- TSPPSLFKTGLPPSRRLPGAIDVIGQTITISRVEG ----------------------------------- ----------------------------------- RRRANENSNIQVLSERSATEVDNNFSKPPPFFPPG ----------------------------------- ------------------------NNNNNNNNNNN APPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN APPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPH ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN LPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRD ----------------------------------- NNNNNNNNNNN-----------NNNNNNNNNNNNN RERDRDRDRERERTRERERERDHSPTPSVFNSDEE -----------HH---HH----------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RYRYREYAERGYERHRASREKEERHRERRHREKEE HH-HHHHH----HH-----HHHHHHHHHH-HH--- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GKEAGSEPAPEQESTEATPAE --------------------- NNNNNNNNNNNNNNNN-----
CPSF6	288	157-445	3.47	3.47	0.0	91.67	1........10........20........30.... TPCNKQFLSQFEMQSRKTTQSGQMSGEGKAGPPGG ----------------------------------- ------------------------NNNNNNNNNNN SSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPL ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGRE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN MDTARTPLSEAEFEEIMNRNRAISSSAISRAVSDA ------------HHHHH---------HHHH----- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SAGDYGSA -------H NNNNNNNN
PAPOLA	253	493-746	1.19	0.0	1.19	92.09	1........10........20........30.... LHQLLPNHVLQKKKKHSTEGVKLTALNDSSLDLSM ----------------------------------- ----------------NNNNNNNNNNNNNNNNNNN DSDNSMSVPSPTSATKTSPLNSSGSSQGRNSPAPA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN VTAASVTNIQATEVSVPQVNSSESSGGTSSESIPQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TATQPAISPPPKPTVSRVVSSTRLVNPPPRSSGNA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ATSGNAATKIPTPIVGVKRTSSPHKEESPKKTKTE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EDETSEDANCLALSGHDKTEAKEQLDTETSTTQSE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TIQTAASLLASQKTSSTDLSDIPALPANPIPVIKN ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SIKLRLNR --EEE--- NNNN----
PAPOLG	245	492-737	1.63	0.0	1.63	61.22	1........10........20........30.... LHHYLPAEILQKKKKQSLSDVNRSSGGLQSKRLSL ----------------------------------- ----------------NNNNNNNNNNNNNNNNNNN DSSCLDSSRDTDNGTPFNSPASKSDSPSVGETERN ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SAEPAAVIVEKPLSVPPAQGLSIPVIGAKVDSTVK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TVSPPTVCTIPTVVGRNVIPRITTPHNPAQGQPHL ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NGMSNITKTVTPKRSHSPSIDGTPKRLKDVEKFIR ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNN--------- LESTFKDPRTAEERKRKSVDAIGGESMPIPTIDTS ----------------------------------- ----------------------------------- RKKRLPSKELPDSSSPVPANNIRVIKNSIRLTLNR ----------------------------EEEE--- -----------------------------------
PABP-4 iso 3	242	368-610	16.94	16.94	0.0	91.32	1........10........20........30.... AQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQ ----HHHHHHHHHHHHHHH---------------- ----------------NNNNNNNNNNNNNNNNNNN PAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRW ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN QQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ASRGLPTTTQRVGSECPDRLAMDFGGAGAAQQGLT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DSCQSGGVPTAVQNLAPRAAVAAAAPRAVAPYKYA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAA -----------------------------HHHHH- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN APPQEQKQMLGERLFPLIQTMHSNLAGKITGM --HHHHHHHHHHHHHHHHHHH---------HH NNNNNNNNNNNNNNNNNNNNNNNNNNN-----
TUT1	236	627-863	22.03	17.8	4.24	96.61	1........10........20........30.... FREALGCHIEQATKRTRSEGGGTGESSQGGTSKRL HHHHH------------------------------ NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KVDGQKNCCEEGKEEQQGCAGDGGEDRVEEMVIEV ----------------------------HH----- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GEMVQDWAMQSPGQPGDLPLTTGKHGAPGEEGQPS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN HAALAERGPKGHEAAQEWSQGEAGKGASLPSSASW ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RCALWHRVWQGRRRARRRLQQQTKEGAGGGAGTRA -------HH--HHHHHHHHHHHHH----------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GWLATEAQVTQELKGLSGGEERPETEPLLSFVASV -HHHHHHHHHHHHH--------------EEEEE-- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SPADRMLTVTPLQDPQGLFPDLHHFL -----EEEEE---------HHHHHHH NNNNNNNNNNNNNNNNNN--------
CPSF6 iso 3	213	160-373	4.69	4.69	0.0	92.02	1........10........20........30.... NKQFLSQFEMQSRKTTQSGQMSGEGKAGPPLAGPP ----------------------------------- -----------------NNNNNNNNNNNNNNNNNN NRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN YGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTL ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN APPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTART ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYG ------HHHHH---------HHH------------ NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SAI -HH NNN
PAPD1 iso 2	211	1-212	15.17	13.27	1.9	85.31	1........10........20........30.... MAWAKKVGGRAGQGRSLSRCDPIILDPEWLYGPPE --HHHH----------------------------- ---NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GEGGPEGVGGETRASIHPPLRTGRHHQKVNHNIRG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PEGSAKDAAPGGGGHHQAGPGQRGDEDGALQHLCG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GGGGVGVSVGRGTGTSVAAEHPSLQVKLLELQELV ------------------------HHHHHHHHHHH NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN LRLAGDHNEGHGKFLAAAQNPADDPAPGAPAPQEL HH--------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GAADKQGGFEDKIPKRRFSEMQNERREQAQRTVLI -----------------HHHHHHHHHHH---EEEE NNNNNNNN--------------------------- H - -
CPSF7	210	160-370	8.57	8.57	0.0	74.29	1........10........20........30.... ATRQNLSQFEAQARKRECVRVPRGGIPPRAHSRDS ------HHHHHH----------------------- ------------------NNNNNNNNNNNNNNNNN SDSADGRATPSENLVPSSARVDKPPSVLPYFNRPP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN HLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN- AEFEDIMKRNRAISSSAISKAVSGASAGDYSDAIE ---HHHH---------HH-HH----------HHHH -----------------------------------
CPSF7 iso 3	209	204-413	8.13	8.13	0.0	74.64	1........10........20........30.... TRQNLSQFEAQARKRECVRVPRGGIPPRAHSRDSS ------HHHHHH----------------------- -----------------NNNNNNNNNNNNNNNNNN DSADGRATPSENLVPSSARVDKPPSVLPYFNRPPS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQH ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN LMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPN ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ATVGPPPDTYMKASAPYNHHGSRDSGPPPSTVSEA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN-- EFEDIMKRNRAISSSAISKAVSGASAGDYSDAIE -HHHHH---------HH-------------HHHH ----------------------------------
PABP-4	207	372-579	16.91	16.91	0.0	90.82	1........10........20........30.... EERKAHLTNQYMQRVAGMRALPANAILNQFQPAAG HHHHHHHHHHHHHHH-------------------- --------NNNNNNNNNNNNNNNNNNNNNNNNNNN GYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGG ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RPQGFQGMPSAIRQSGPRPTLRHLAPTGSECPDRL ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN AMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN VAAAAPRAVAPYKYASSVRSPHPAIQPLQAPQPAV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN HVQGQEPLTASMLAAAPPQEQKQMLGERLFPL ---------HHHHH---HHHHHHHHHHHHHHH NNNNNNNNNNNNNNNNNNNNN-----------
CPSF7 iso 2	201	159-360	10.95	10.95	0.0	74.13	1........10........20........30.... PATRQNLSQFEAQARKRIPPRAHSRDSSDSADGRA --------HHHHHH--------------------- -----------------NNNNNNNNNNNNNNNNNN TPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGL ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PPPPIPPPPPLSSSFGVPPPPPGIHYQHLMPPPPR ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN LPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DTYMKASAPYNHHGSRDSGPPPSTVSEAEFEDIMK ----------------------------HHHHHHH NNNNNNNNNNNNNNNNNNNNNNNNNN--------- RNRAISSSAISKAVSGASAGDYSDAI --------HHHHH---------HHHH --------------------------
FIP1L1 iso 4	199	180-379	1.51	1.51	0.0	49.75	1........10........20........30.... IRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDG HHH-------------------------------- ----------------------------------N RFNLFKVQQGRTGNSEKETALPSTKAEFTSPPSLF ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRY ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNN-------- GRAESPDLRRLPGAIDVIGQTITISRVEGRRRANE ----------------------------------- ----------------------------------- NSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHL ----------------------------------- ---------------------NNNNNNNNNNNNNN PPPPFLPPPPTVSTAPPLIPPPGK ------------------------ NNNNNNNNNNNNNNNNNNNNNN--
PABP-1	198	369-567	16.16	16.16	0.0	88.89	1........10........20........30.... QRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPA ---HHHHHHHHHHHHHHH----------------- ------------NNNNNNNNNNNNNNNNNNNNNNN PPSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN AQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PRVMSTQRVANTSTQTMGPRPAAAAAAATPAVRTV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PLTASMLASAPPQEQKQMLGERL ---HHHHH---HHHHHHHHHHHH NNNNNNNNNNNNN----------
Symplekin	196	1079-1275	14.29	12.76	1.53	89.29	1........10........20........30.... VRSFTPHQQAHIPNSIMTILEASGKQEPEAKEAPA HHH----------HHHHHHHH-------------- -------------------NNNNNNNNNNNNNNNN GPLEEDDLEPLTLAPAPAPRPPQDLIGLRLAQEKA ---------------------------H----HHH NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN LKRQLEEEQKLKPGGVGAPSSSSPSPSPSARPGPP HHH--HH---------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PSEEAMDFREEGPECETPGIFISMDDDSGLTEAAL --------------------EEE--------HHHH NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN LDSSLEGPLPKETAAGGLTLKEERSPQTLAPVGED H---------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN AMKTPSPAAEDAREPEAKGNS --------------------- NNNNNNNNNNNNNNNNNNN--
PABP-3	194	368-562	17.01	17.01	0.0	77.84	1........10........20........30.... AQRKEERQAYLTNEYMQRMASVRAVPNQRAPPSGY ----HHHHHHHHHHHHHHHH--------------- ----------------------------------- FMTAVPQTQNHAAYYPPSQIARLRPSPRWTAQGAR ----------------------------------- ---NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PHPFQNKPSAIRPGAPRVPFSTMRPASSQVPRVMS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TQRVANTSTQTVGPRPAAAAAAAATPAVRTVPRYK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN YAAGVRNPQQHRNAQPQVTMQQLAVHVQGQETLTA ----------------------------------H NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SRLASAPPQKQKQMLGERL HHHH---HHHHHHHHHHHH NNNNNNNNNNNNNN-----
PABP-4 iso 2	194	369-563	15.98	15.98	0.0	90.21	1........10........20........30.... QRKEERKAHLTNQYMQRVAGMRALPANAILNQFQP ---HHHHHHHHHHHHHH------------------ ---------NNNNNNNNNNNNNNNNNNNNNNNNNN AAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQ ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN QGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGNAPA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SRGLPTTTQRVGVPTAVQNLAPRAAVAAAAPRAVA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PYKYASSVRSPHPAIQPLQAPQPAVHVQGQEPLTA ----------------------------------H NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SMLAAAPPQEQKQMLGERL HHHH---HHHHHHHHHHHH NNNNNNNNN----------
PABP-2	164	1-165	25.61	25.61	0.0	99.39	1........10........20........30.... MAAAAAAAAAAGAAGGRGSGPGRRRHLVPGAGGEA --HHHHHHHHH------------------------ -NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GEGAPGGAGDYGNGLESEELEPEELLLEPEPEPEP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EGDPGDGAIEDPELEAIKARVREMEEEAEKLKELQ -----------HHHHHHHHHHHHHHHHHHHHHHHH NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NEVEKQMNMSPPPGNAGPVIMSIE HHHHHHH---------------HH NNNNNNNNNNNNNNNNNNNNNNNN
PABP-2 iso 2	164	1-165	25.0	25.0	0.0	99.39	1........10........20........30.... MAAAAAAAAAAGAAGGRGSGPGRRRHLVPGAGGEA --HHHHHHHHH------------------------ -NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GEGAPGGAGDYGNGLESEELEPEELLLEPEPEPEP ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLV ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EGDPGDGAIEDPELEAIKARVREMEEEAEKLKELQ -----------HHHHHHHHHHHHHHHHHHHHHHHH NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NEVEKQMNMSPPPGNAGPVIMSIE HHHHHH----------------HH NNNNNNNNNNNNNNNNNNNNNNNN
PAPD4	144	1-145	0.0	0.0	0.0	13.19	1........10........20........30.... MFPNSILGRPPFTPNHQQHNNFFTLSPTVYSHQQL ----------------------------------- ----------------------------------- IDAQFNFQNADLSRAVSLQQLTYGNVSPIQTSASP ----------------------------------- ----------------------------------- LFRGRKRLSDEKNLPLDGKRQRFHSPHQEPTVVNQ ----------------------------------- ----------------------------------- IVPLSGERRYSMPPLFHTHYVPDIVRCVPPFREIA ----------------------------------- --------------------NNNNNNNNNNNNNNN FLEP ---- NNNN
PAPOLB	139	498-637	1.44	0.0	1.44	0.0	1........10........20........30.... PHHVLQDKKAHSTEGRRLTDLNDSSFDLSAGCENS ----------------------------------- ----------------------------------- MSVPSSTSTMKTGPLISSSQGRNSPALAVMTASVA ----------------------------------- ----------------------------------- NIQATEFSLQQVNTNESSGVALNESIPHAVSQPAI ----------------------------------- ----------------------------------- SPSPKAMVARVVSSTCLISHPDLQETQQQTYLIL -------------------------------EE- ----------------------------------
CPSF2	133	395-528	37.59	27.82	9.77	49.62	1........10........20........30.... YLEKEKLKKEAAKKLEQSKEADIDSSDESDIEEDI HHHHHHHHHHHHHHHHH-----------HHHHHH- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DQPSAHKTKHDLMMKGEGSRKGSFFKQAKKSYPMF ----------EEEE---------HHHHHH------ NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN---- PAPEERIKWDEYGEIIKPEDFLVPELQATEEEKSK --------------EE-------------HHHHHH ----------------------------------- LESGLTNGDEPMDQDLSDVPTKCISTTE HH-------------------EEEEEEE ----------------------------
PAPD4 iso 2	122	1-123	0.82	0.82	0.0	0.0	1........10........20........30.... MFPNSILGRPPFTPNHQQHNNFFTLSPTVYSHQQL ----------------------------------H ----------------------------------- IDAQFNFQNADLSRAVSLQQLTYGNVSPIQTSASP ----------------------------------- ----------------------------------- LFRGRKRLSDEKNLPLDGKRQRFHSPHQEPTVVNQ ----------------------------------- ----------------------------------- IVPLSGERRYSMPPLFH ----------------- -----------------
FIP1L1	122	1-123	15.57	12.3	3.28	98.36	1........10........20........30.... MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHV --HHHHHHHHHHH---------HHHH--------- --NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN HSDLAKDLDENEVERPEEENASANPPSGIEDETAE ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKT --------------------------EEEE----- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GAPQYGSYGTAPVNLNI ----------------- NNNNNNNNNNNNNNNNN
CPSF7 iso 3	116	1-117	6.9	0.0	6.9	31.03	1........10........20........30.... MGRPESAGGGSRGPFEGGGRARRAGGIFLTLSILR --------------------------EEEEEEEE- -NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TRDLPSGAMSEGVDLIDIYADEEFNQDPEFNNTDQ ----------------------------------- NN--------------------------------- IDLYDDVLTATSQPSDDRSSSTEPPPPVRQEPSPK ----------------------------------- ----------------------------------- PNNKTPAILYT ----------- -----------
TUT1	114	222-336	9.65	6.14	3.51	100.0	1........10........20........30.... DLGDLEEPQPVPKAPESPSLDSALASPLDPQALAC ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TPASPPDSQPPASPQDSEALDFETPSSSLAPQTPD ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SALASETLASPQSLPPASPLLEDREEGDLGKASEL HHHHH-------------------------EEEE- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN AETPKEEKA -------HH NNNNNNNNN
PABP-1 iso 2	111	369-480	21.62	21.62	0.0	96.4	1........10........20........30.... QRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPA ---HHHHHHHHHHHHHH------------------ ----NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PPSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWT ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN AQGARPHPAVHVQGQEPLTASMLASAPPQEQKQML ----------------------------HHH--H- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GERLFP HHHHHH NNNNNN
FIP1L1 iso 4	108	1-109	17.59	12.96	4.63	98.15	1........10........20........30.... MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVER ---HHHHHHHHHH--------HHHH---------- --NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PEEENASANPPSGIEDETAENGVPKPKVTETEDDS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL ----------EEEEE-------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NIK --- NNN
CPSF4	107	163-270	2.8	0.0	2.8	67.29	1........10........20........30.... KFMHPRFELPMGTTEQPPLPQQTQPPAKQSNNPPL ----------------------------------- --------NNNNNNNNNNNNNNNNNNNNNNNNNNN QRSSSLIQLTSQNSSPNQQRTPQVIGVMQSQNSSA ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GNRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLS -----------EEE--------------------- NNNNNNNNNN------------------------- GQ -- --
Symplekin iso 2	104	449-553	16.35	16.35	0.0	0.0	1........10........20........30.... LARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVK HHHHHHH---------------------------- ----------------------------------- TESVLIKRRLSAQGQAISVVGSLSSMSPLEEEAPQ --HHHHH---------------------------- ----------------------------------- AKRRPEPIIPVTQPRLAGAGGRKKIFRLSDVLKP ----------------------HHHH--H----- ----------------------------------
FIP1L1 iso 3	103	1-104	16.5	11.65	4.85	98.06	1........10........20........30.... MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVER ----HHHHHHHH---------HHHH---------- --NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PEEENASANPPSGIEDETAENGVPKPKVTETEDDS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPV ----------EEEEE------------------ NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Symplekin	103	449-552	14.56	14.56	0.0	0.0	1........10........20........30.... LARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVK HHHHHHH---------------------------- ----------------------------------- TESVLIKRRLSAQGQAISVVGSLSSMSPLEEEAPQ ----HH----------------------------- ----------------------------------- AKRRPEPIIPVTQPRLAGAGGRKKIFRLSDVLK ----------------H-----HHHHH------ ---------------------------------
CPSF6 iso 3	98	381-479	17.35	17.35	0.0	94.9	1........10........20........30.... LIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSG HH--------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRE ------------------------------HHHHH NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RSRERERHRDRDRDRDRERDREREYRHR H-HHHH--------------HHHHH--- NNNNNNNNNNNNNNNNNNNNNNN-----
CPSF6	93	459-552	27.96	27.96	0.0	100.0	1........10........20........30.... KVSADDRCKVLISSLQDCLHGIESKSYGSGSRRER -----HHHHHHHHHHHHH----------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SRERDHSRSREKSRRHKSRSRDRHDDYYRERSRER --------------------------HHHHH-HHH NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ERHRDRDRDRDRERDREREYRHR ---------------HHHHH--- NNNNNNNNNNNNNNNNNNNNNNN
RBBP6	89	75-164	19.1	14.61	4.49	73.03	1........10........20........30.... IPIGGVKSTSKTYVISRTEPAMATTKAIDDSSASI E-----------EEE-------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SLAQLTKTANLAEANASEEDKIKAMMSQSGHEYDP ----------HHH----HHHHHHHHHH-------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNN----- INYMKKPLGPPPPSYTCFR ------------------- -------------------
RBBP6 iso 2	88	76-164	21.59	15.91	5.68	72.73	1........10........20........30.... PIGGVKSTSKTYVISRTEPAMATTKAIDDSSASIS -----------EEE--------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN LAQLTKTANLAEANASEEDKIKAMMSQSGHEYDPI ---------HHH----HHHHHHHHHHH-------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNN------ NYMKKPLGPPPPSYTCFR --------------EE-- ------------------
RBBP6 iso 4	88	76-164	18.18	14.77	3.41	72.73	1........10........20........30.... PIGGVKSTSKTYVISRTEPAMATTKAIDDSSASIS -----------EE---------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN LAQLTKTANLAEANASEEDKIKAMMSQSGHEYDPI ---------HHH----HHHHHHHHHH--------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNN------ NYMKKPLGPPPPSYTCFR --------------E--- ------------------
CPSF4 iso 3	81	163-244	3.7	0.0	3.7	0.0	1........10........20........30.... KFMHPRFELPMGTTEQPPLPQQTQPPAKRTPQVIG ----------------------------------- ----------------------------------- VMQSQNSSAGNRGPRPLEQVTCYKCGEKGHYANRC --------------------EEE------------ ----------------------------------- TKGHLAFLSGQ ----------- -----------
CPSF4 iso 2	79	166-245	3.8	0.0	3.8	0.0	1........10........20........30.... HPRFELPMGTTEQPPLPQQTQPPAKQRTPQVIGVM ----------------------------------- ----------------------------------- QSQNSSAGNRGPRPLEQVTCYKCGEKGHYANRCTK ------------------EEE-------------- ----------------------------------- GHLAFLSGQ --------- ---------
PCF11	79	1477-1556	11.39	11.39	0.0	0.0	1........10........20........30.... SCYEDYQNTSSFDCTPSPSKTPVENPLNIMLNIVK --HH-----------------------HHHHHHH- ----------------------------------- NELQEPCDSPKVKEERIDTPPACTEESIATPSEIK ----------------------------------- ----------------------------------- TENDTVESV --------- ---------
PAPD1	78	1-79	17.95	15.38	2.56	0.0	1........10........20........30.... MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGT ----------------------------------- ----------------------------------- VAKDLRRDEQPSGSVETGFEDKIPKRRFSEMQNER ---------------------------HHHHHHHH ----------------------------------- REQAQRTV HHHH--EE --------
CPSF2	77	640-717	6.49	2.6	3.9	0.0	1........10........20........30.... SKVDTGVILEEGELKDDGEDSEMQVEAPSDSSVIA ----------------------------------- ----------------------------------- QQKAMKSLFGDDEKETGEESEIIPTLEPLPPHEVP -HH-------------------------------- ----------------------------------- GHQSVFM ----EEE -------
CPSF7 iso 3	77	438-515	20.78	20.78	0.0	74.03	1........10........20........30.... SLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPS -HHHH------------------------------ --------------------NNNNNNNNNNNNNNN RSRESSRRHRDLLHNEDRHDDYFQERNREHERHRD --------------------HHHHHHHHHHHH--- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RERDRHH ------- NNNNNNN
RBBP6	77	176-253	20.78	10.39	10.39	0.0	1........10........20........30.... TNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGA ------------------------E---------E ----------------------------------- MLTNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSS EE-----EEEE---HHHHHHH-H------------ ----------------------------------- SSEEDDP ------- -------
RBBP6 iso 2	77	176-253	23.38	12.99	10.39	0.0	1........10........20........30.... TNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGA ---------------------HH-E---------E ----------------------------------- MLTNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSS EE-----EEEE---HHHHHHH-H------------ ----------------------------------- SSEEDDP ------- -------
RBBP6 iso 4	77	176-253	19.48	11.69	7.79	0.0	1........10........20........30.... TNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGA ----------------------------------E ----------------------------------- MLTNTGKYAIPTIDAEAYAIGKKEKPPFLPEEPSS EE-----EEE----HHHHHHHHH------------ ----------------------------------- SSEEDDP ------- -------
CPSF7	76	396-472	13.16	13.16	0.0	75.0	1........10........20........30.... LKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSR HHHH------------------------------- -------------------NNNNNNNNNNNNNNNN SRESSRRHRDLLHNEDRHDDYFQERNREHERHRDR -------------------H----H-HHHH----- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ERDRHH ------ NNNNNN
CPSF7 iso 2	74	389-463	13.51	13.51	0.0	77.03	1........10........20........30.... DCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSR HH--------------------------------- -----------------NNNNNNNNNNNNNNNNNN ESSRRHRDLLHNEDRHDDYFQERNREHERHRDRER ---------------------HHHHHHHH------ NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DRHH ---- NNNN
PABP-2 iso 3	73	261-334	6.85	0.0	6.85	80.82	1........10........20........30.... ESLFRGRQIKVIPKRTNRPGISTTDRGFPRARYRA -------EEEEE----------------------- --------------NNNNNNNNNNNNNNNNNNNNN RTTNYNSSRSRFYSGFNSRPRGRVYRGRARATSWY ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SPY --- NNN
CPSF7	71	1-72	0.0	0.0	0.0	0.0	1........10........20........30.... MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVL ----------------------------------- ----------------------------------- TATSQPSDDRSSSTEPPPPVRQEPSPKPNNKTPAI ----------------------------------- ----------------------------------- L - -
CPSF7 iso 2	71	1-72	0.0	0.0	0.0	0.0	1........10........20........30.... MSEGVDLIDIYADEEFNQDPEFNNTDQIDLYDDVL ----------------------------------- ----------------------------------- TATSQPSDDRSSSTEPPPPVRQEPSPKPNNKTPAI ----------------------------------- ----------------------------------- L - -
Symplekin iso 2	71	328-399	22.54	22.54	0.0	100.0	1........10........20........30.... LGTPQAEIARNMPSSKDTRKRPRDDSDSTLKKMKL H---HHHHHHH-----------------HHHHHH- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EPNLGEDDEDKDLEPGPSGTSKASAQISGQSDTDI ----------------------------------H NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN T H N
Symplekin	70	330-400	24.29	24.29	0.0	100.0	1........10........20........30.... TPQAEIARNMPSSKDTRKRPRDDSDSTLKKMKLEP --HHHHHHHH----------------HHHHHH--- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NLGEDDEDKDLEPGPSGTSKASAQISGQSDTDITA --------------------------------HHH NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
CPSF1	69	709-778	4.35	2.9	1.45	100.0	1........10........20........30.... TTESRLGGARDELGGRSGPEAEGLGSETSPTVDDE E---------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN EEMLYGDSGSLFSPSKEEARRSSQPPADRDPAPF -HH------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
CSTF3	69	649-718	17.39	17.39	0.0	76.81	1........10........20........30.... PNTVEEAVRIITGGAPELAVEGNGPVESNAVLTKA -------H--------------------------- ---NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN VKRPNEDSDEDEEKGAVVPPVHDIYRARQQKRIR ---------------------HHHHHHHHHHH-- NNNNNNNNNNNNNNNNNNNNN-------------
CPSF6	69	1-70	0.0	0.0	0.0	0.0	1........10........20........30.... MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDD ----------------------------------- ----------------------------------- VISPSANNGDAPEDRDYMDTLPPTVGDDVGKGAA ---------------------------------- ----------------------------------
CPSF6 iso 3	69	1-70	1.45	1.45	0.0	0.0	1........10........20........30.... MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDD ----------------H------------------ ----------------------------------- VISPSANNGDAPEDRDYMDTLPPTVGDDVGKGAA ---------------------------------- ----------------------------------
CSTF3	61	550-611	8.2	8.2	0.0	100.0	1........10........20........30.... SRAKLAAIIPDPVVAPSIVPVLKDEVDRKPEYPKP HHHHH------------------------------ NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN DTQQMIPFQPRHLAPPGLHPVPGGVF -------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNN
PABP-2	59	248-307	0.0	0.0	0.0	100.0	1........10........20........30.... RTNRPGISTTDRGFPRARYRARTTNYNSSRSRFYS ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GFNSRPRGRVYRGRARATSWYSPY ------------------------ NNNNNNNNNNNNNNNNNNNNNNNN
TUT1	57	102-159	35.09	35.09	0.0	100.0	1........10........20........30.... VGAREAVLSQSQHSLGGHRLRVRPREQKEFQSPAS HHHHHHHHH-------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN KSPKGAAPDSHQLAKALAEAAD ---------HHHHHHHHHHH-- NNNNNNNNNNNNNNNNNNNNNN
CPSF6 iso 2	54	16-70	5.56	5.56	0.0	0.0	1........10........20........30.... EEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDR HHH-------------------------------- ----------------------------------- DYMDTLPPTVGDDVGKGAA ------------------- -------------------
PAPD1	53	530-583	20.75	20.75	0.0	96.23	1........10........20........30.... LLLPSAPNRKSFTKKKSNKFAIETVKNLLESLKGN H--------------------HHHHHHHHHH---- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN RTENFTKTSGKRTISTQT ------------------ NNNNNNNNNNNNNNNN--
CPSF3	53	632-685	62.26	33.96	28.3	0.0	1........10........20........30.... DSILSVTVDGKTANLNLETRTVECEEGSEDDESLR --EEEEEE---EEEEE----EEEE------HHHHH ----------------------------------- EMVELAAQRLYEALTPVH HHHHHHHHHHHHH----- ------------------
CSTF2	53	93-146	37.74	37.74	0.0	0.0	1........10........20........30.... ASEKNKEELKSLGTGAPVIESPYGETISPEDAPES ------HHHH-----------------------HH ----------------------------------- ISKAVASLPPEQMFELMK HHHHH----HHHHHHHHH ------------------
PAPD1 iso 2	52	661-713	21.15	21.15	0.0	96.15	1........10........20........30.... LLPSAPNRKSFTKKKSNKFAIETVKNLLESLKGNR --------------------HHHHHHHHHHH---- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN TENFTKTSGKRTISTQT ----------------- NNNNNNNNNNNNNNN--
TUT1	52	1-53	50.0	32.69	17.31	0.0	1........10........20........30.... MAAVDSDVESLPRGGFRCCLCHVTTANRPSLDAHL ----------------EEEEEEEEE---HHHHHHH ----------------------------------- GGRKHRHLVELRAARKA -------HHHHHHHHHH -----------------
PABP-2 iso 2	51	246-297	0.0	0.0	0.0	100.0	1........10........20........30.... PKRTNRPGISTTDRGFPRARYRARTTNYNSSRSRF ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN YSGFNSRPRGRVYRSG ---------------- NNNNNNNNNNNNNNNN
PAPD1	50	123-173	10.0	10.0	0.0	0.0	1........10........20........30.... SIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQT -HHHHH----------------------------- ----------------------------------- SERSRVRSSNQLPRS --------------- ---------------
PAPD1 iso 2	50	253-303	12.0	12.0	0.0	0.0	1........10........20........30.... SIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKNQT HHHHHH----------------------------- ----------------------------------- SERSRVRSSNQLPRS --------------- ---------------
CSTF2 iso 2	49	93-142	30.61	30.61	0.0	0.0	1........10........20........30.... ASEKNKEELKSLGTGAPVIESPYGETISPEDAPES -------HHH-----------------------HH ----------------------------------- ISKAVASLPPEQMF HHHHH----HHHHH --------------
PCF11	49	1395-1444	55.1	53.06	2.04	0.0	1........10........20........30.... EEIADLEERAKSQFFEKVHEEVVLKTQEAAKEKEF HHHH-HHHHH---HHHHHHHHHHHHHHHHH----- ----------------------------------- QSVPAGPAGAVESC -E------------ --------------
PABP-4 iso 3	46	615-661	73.91	73.91	0.0	60.87	1........10........20........30.... NSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAA HHHHHHHH--HHHHHHHHHHHHHHHHHHHH-H-HH ----------------NNNNNNNNNNNNNNNNNNN QKVGAVAAATS HHH-------- NNNNNNNNN--
CPSF1	46	881-927	13.04	0.0	13.04	93.48	1........10........20........30.... SQLGQGNLKVRFKKVPHNINFREKKPKPSKKKAEG --------EEEEEE--------------------- ---NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN GGAEEGAGARG ----------- NNNNNNNNNNN
PABP-1 iso 2	45	503-548	57.78	57.78	0.0	0.0	1........10........20........30.... ELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKA HHHHHH--HHHHHHHHHHHHHHHHHHHH------- ----------------------------------- VNSATGVPTV ---------- ----------
TUT1	45	577-622	11.11	11.11	0.0	100.0	1........10........20........30.... LQYQRRSSRGRDWGLLPLLQPSSPSSLLSATPIPL H---------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN PLAPFTQLTA ------HHHH NNNNNNNNNN
CSTF2T	45	92-137	26.67	26.67	0.0	0.0	1........10........20........30.... AASEKNKEELKSLGPAAPIIDSPYGDPIDPEDAPE ------HHHHH----------------------HH ----------------------------------- SITRAVASLP HHHHH----- ----------
PABP-1	44	593-637	65.91	65.91	0.0	0.0	1........10........20........30.... LLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAV HHHHH--HHHHHHHHHHHHHHHHHHHHHHHH---- ----------------------------------- NSATGVPTV --------- ---------
PABP-4	43	602-645	69.77	69.77	0.0	65.12	1........10........20........30.... LLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKV HHHHH--HHHHHHHHHHHHHHHHHHHH-H-HHHH- -------------NNNNNNNNNNNNNNNNNNNNNN GAVAAATS -------- NNNNNN--
PABP-4 iso 2	43	589-632	74.42	74.42	0.0	65.12	1........10........20........30.... LLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKV HHHHH--HHHHHHHHHHHHHHHHHHHHHH-HHHHH -------------NNNNNNNNNNNNNNNNNNNNNN GAVAAATS -------- NNNNNN--
PABP-3	42	590-632	59.52	59.52	0.0	0.0	1........10........20........30.... YMLESPESLRSKVDEAVAVLQAHQAKEATQKAVNS HHH--HHHHHHHHHHHHHHHHHHHH-H---H---- ----------------------------------- ATGVPTV ------- -------
PABP-1	41	250-291	53.66	36.59	17.07	0.0	1........10........20........30.... EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMK HH---EE---EEEEE------HHHHHHHHHHHHH- ----------------------------------- QDRITR ------ ------
PABP-1 iso 2	41	250-291	53.66	34.15	19.51	0.0	1........10........20........30.... EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMK HH---EE---EEEEEE------HHHHHHHHHHHH- ----------------------------------- QDRITR ------ ------
PABP-2 iso 3	41	155-196	58.54	58.54	0.0	0.0	1........10........20........30.... EMEEEAEKLKELQNEVEKQMNMSPPPGNAGPVIMS HHHHHHHHHHHHHHHHHHH---------------- ----------------------------------- IEEKME HHHHH- ------
PABP-3	41	250-291	56.1	36.59	19.51	0.0	1........10........20........30.... EMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMK HH---EE---EEEEEE----HHHHHHHHHHHHH-- ----------------------------------- QDRITR ------ ------
CPSF1	40	401-441	0.0	0.0	0.0	100.0	1........10........20........30.... QEPPASAVREAADKEEPPSKKKRVDATAGWSAAGK ----------------------------------- NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN SVPQD ----- NNNNN
WDR33	39	1-40	0.0	0.0	0.0	0.0	1........10........20........30.... MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQ ----------------------------------- ----------------------------------- QAMQ ---- ----
Symplekin iso 2	35	639-674	22.86	22.86	0.0	0.0	1........10........20........30.... LCWRRHSSQRVPWRWSASTARMRVAPIWACPHFET --------------H-HHHHHHH------------ -----------------------------------
WDR33 iso 2	32	1-33	0.0	0.0	0.0	0.0	1........10........20........30. MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDF -------------------------------- --------------------------------
CPSF5	31	1-32	0.0	0.0	0.0	0.0	1........10........20........30 MSVVPPNRSQTGWPRGVTQFGNKYIQQTKPL ------------------------------- -------------------------------
RPB1	31	154-185	0.0	0.0	0.0	0.0	1........10........20........30 CEGGEEMDNKFGVEQPEGDEDLTKEKGHGGC ------------------------------- -------------------------------
PAPOLA	30	1-31	0.0	0.0	0.0	0.0	1........10........20........3 MPFPVTTQGSQQTQPPQKHYGITSPISLAA ------------------------------ ------------------------------
Symplekin	30	1-31	13.33	13.33	0.0	0.0	1........10........20........3 MASGSGDSVTRRSVASQFFTQEEGPGIDGM --------------HHHH------------ ------------------------------
Symplekin iso 2	30	1-31	20.0	20.0	0.0	0.0	1........10........20........3 MASGSGDSVTRRSVASQFFTQEEGPGIDGM -------------HHHHHH----------- ------------------------------
WDR33 iso 3	30	1-31	0.0	0.0	0.0	0.0	1........10........20........3 MATEIGSPPRFFHMPRFQHQAPRQLFYKRP ------------------------------ ------------------------------
PP-1A	30	301-331	0.0	0.0	0.0	0.0	1........10........20........3 KNKGKYGQFSGLNPGGRPITPPRNSAKAKK ------------------------------ ------------------------------
PP-1A iso 2	30	312-342	0.0	0.0	0.0	0.0	1........10........20........3 KNKGKYGQFSGLNPGGRPITPPRNSAKAKK ------------------------------ ------------------------------
PAPOLB	29	1-30	0.0	0.0	0.0	27.59	1........10........20........ MPFPVTTQGPPQPAPPPNRYGVSSPISLA ----------------------------- ---------------------NNNNNNNN
PP-1B	28	300-328	0.0	0.0	0.0	0.0	1........10........20....... KKAKYQYGGLNSGRPVTPPRTANPPKKR ---------------------------- ----------------------------
CPSF1	27	543-570	0.0	0.0	0.0	0.0	1........10........20...... RKEEEDNPKGEGTEQEPSTTPEADDDG --------------------------- ---------------------------
CLP1 iso 2	27	1-28	40.74	0.0	40.74	0.0	1........10........20...... MGEEANDDKKPTTKFELERETELRFEV ------------EEEEE----EEEEEE ---------------------------
RBBP6 iso 3	27	80-107	14.81	0.0	14.81	0.0	1........10........20...... VKSTSKTYVISRTEPAMATTKAVCKNT ------EEEE----------------- ---------------------------
PABP-5	25	277-302	56.0	56.0	0.0	0.0	1........10........20.... KIERLAELRRRFERLRLKEKSRPPG ---HHHHHHHHHHHHHH-------- -------------------------
PAPOLA iso 2	25	1-26	0.0	0.0	0.0	0.0	1........10........20.... MPFPVTTQGSQQTQPPQKHYGITSP ------------------------- -------------------------
PAPOLG	23	1-24	0.0	0.0	0.0	0.0	1........10........20.. MKEMSANTVLDSQRQQKHYGITS ----------------------- -----------------------
PABP-4	22	269-291	86.36	86.36	0.0	0.0	1........10........20. KVERQAELKRKFEQLKQERISR HHHHHHHHHHHHHHHHHHH--- ----------------------
CPSF1	22	821-843	0.0	0.0	0.0	0.0	1........10........20. SSFGQPTTQGEARREEATRQGE ---------------------- ----------------------
CPSF3	22	587-609	13.64	13.64	0.0	0.0	1........10........20. VQSNPKIRKGAVQKVSKKLEMH H-------------------HH ----------------------
CLP1	22	1-23	27.27	0.0	27.27	0.0	1........10........20. MGEEANDDKKPTTKFELERETE ------------EEEEE----E ----------------------
PABP-4 iso 2	21	269-290	61.9	61.9	0.0	0.0	1........10........20 KVERQAELKRKFEQLKQERIS --HHHHHHHHHHHHH------ ---------------------
PABP-4 iso 3	21	269-290	52.38	52.38	0.0	0.0	1........10........20 KVERQAELKRKFEQLKQERIS ---HHHHHHHHHHH------- ---------------------

Contact: Lukasz Kozlowski

This work was supported by Polish Ministry of Science and Higher Education (grant NN301 190139).